The POLR2L antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to POLR2L, and RNA polymerase II, I and III subunit L. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The POLR2L antibody has been validated for the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2L/RBP10 is part of the core element with the central large cleft(By similarity)